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Science Journal

 

Nature and Science
(Nat Sci
ISSN 1545-0740 (print); ISSN 2375-7167 (online); doi:10.7537, Monthly
Volume 15 - Number 7 (Cumulated No. 124), 25, 2017
Cover (jpg), Cover (pdf), Introduction, Contents, Call for Papers, nsj1507

 

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CONTENTS   

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1

Recent advances in management of idiopathic sudden sensorineural hearing loss by hyperbaric oxygen

 

Mosaad Yehya Elseesy1, Ahmed Soliman Elkady1, Samer Badei kamel1, Ahmed Mostafa Abd Elraouf 2

 

1Department of Otolaryngology, Benha Faculty of Medicine, Benha, Egypt.

2Resident at Otolaryngology Department, Hearing and Speech Institute, Giza, Egypt

Dr.meshoooo@gmail.com

 

Abstract: Idiopathic sudden sensorineural hearing loss (ISSNHL) is a clinical condition with which most otolaryngologists are familiar The treatment of ISSNHL is still a controversy as there is no definitive line of treatment that takes the upper hand in enhancing the hearing threshold of the patients. These lines include short course systemic corticosteroids therapy, intra-tympanic injection of corticosteroids, hyperbaric oxygen and others.

[Mosaad Yehya Elseesy, Ahmed Soliman Elkady, Samer Badei kamel, Ahmed Mostafa Abd Elraouf. Recent advances in management of idiopathic sudden sensorineural hearing loss by hyperbaric oxygen. Nat Sci 2017;15(7):1-4]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 1. doi:10.7537/marsnsj150717.01.

 

Keywords: Sudden – sensorineural – hearing loss – hyperbaric oxygen – corticosteroids

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Post Mastectomy Patients' Perception of Wound Care Learning Needs before Discharge at Oncology Center –Mansoura University, Egypt

 

Karima Elshamy *1, Amal Eid, 1 Heba Mohamed2

 

1Medical Surgical Nursing Department - Faculty of Nursing, Mansoura University, Egypt

2Clinical instructors -Chest Hospital, Mansoura University, Egypt

Karima_elshamy2002@yahoo.com

 

Abstract: Breast cancer is the most common type of cancer affecting women in Egypt, and the second cause of mortality among Egyptian females. Mastectomy is one of the best treatment for breast cancer, it must be followed by necessary instruction to increase knowledge and perception for patients related to wound care to complete its success. Exploratory descriptive design was used to assess post mastectomy patients' perceptions of wound care learning needs before discharge from hospital in the 2nd post operative day at Oncology center – Mansoura University. Subjects and Method: This study was conducted during three months duration from the beginning of August to the end of October 2015 in surgical department at Oncology Center-Mansoura University (OCMU). Ninety mastectomy women were included, based on inclusion criteria. Post mastectomy patients' perception of wound care learning needs tool was used for data collection:, which consists of (79) items, and divided into three main parts, part 1: socio-demographic characteristics and medical data of the patients, part II: patients' knowledge about post mastectomy wound care, and part III: patients' perception about post mastectomy wound care. Results: Nearly half of them were in age group (50-<60), more than half of patients had poor knowledge, and majority of them had low perception about post mastectomy wound care. Conclusions: Mastectomy patients have low perception of wound care learning needs before their discharge. Recommendations: Planned discharge education should be prepared and should be given to women who have mastectomy as well as general education about post mastectomy care.

[Karima Elshamy, Amal Eid, Heba Mohamed. Post Mastectomy Patients' Perception of Wound Care Learning Needs before Discharge at Oncology Center –Mansoura University, Egypt. Nat Sci 2017;15(7):5-16]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 2. doi:10.7537/marsnsj150717.02.

 

Keywords: breast cancer, mastectomy, wound care, perception, learning needs.

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Role of adhesion molecules & IL 1β in peptic ulcer disease

 

Mohamed Nabil Rafat Farahat1, Assem Mahmoud El-Sherif1, Mohamed Said El-Shorbagy2, Mohamed Samy El-Hakim3, Abd El Jawad Said Mohamed1, Zakarya Mohamed Zakarya1 and Ahmed Hassan Amer Khadrawy1.

 

1 Internal Medicine Departement, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

2 Clinical Pathology Departement Faculty of Medicine, Al-Azhar University, Cairo, Egypt

3 Histopathology Departement, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

dr2ahmad2007@yahoo.com

 

Abstract: Background: a peptic ulcer is an excavated defect in the gastric or duodenal mucosa that extends through the muscularis mucosa into the deeper layers of the wall and can lead to hematemesis and perforation. Cytokines and chemokines are small peptide molecules, synthesized and released by nearly all cell types present in the human body. They play a key role as communicators between cells; modulating a wide variety of functions. Cytokines are known to induce, amplify, perpetuate and terminate inflammation. Aim- of this study is to detect if there a role in of the cytokines (specifically interleukin 1 beta) & the adhesion molecules (specifically ICAM-1 & VCAM-1) in cases of peptic ulcer disease along with the presence and absence of H. pylori and the intake of NSAIDs. Patients and methods; This study was conducted during the period from December 2011 to December 2015; on 60 subjects divided as follow; 40 patients who had a history suspected of gastro-dudentis and who attended in the outpatient clinic and inpatient section of internal medicine department in El-Hussein University hospital and Farwaniahospital and were documented to have a peptic ulcer disease. Where 20 patients had a recent attack of peptic ulcer and another 20 patients had a history of recurrent attacks of peptic ulcer disease with detailed history of aspirin intake. Those two groups along with another group of 20 healthy subjects were tested for the presence or absence of H.pylori, serum IL 1B, I-CAM, V-CAM, complete blood count, kidney and liver functions. Results; Showing the highly significance of IL1B, I-CAM and V-CAM levels in patients with peptic ulcer disease. Conclusion; 1) The presence of adhesion molecules (ICAM-1, VCAM-1) and IL-1 beta is significantly correlated with the presence of peptic ulcer disease. 2) The increase the values of adhesion molecules (ICAM-1, VCAM-1) and interleukin 1 beta is correlated with the increase the suspicion of peptic ulcers recurrence.

[Mohamed Nabil Rafat Farahat, Assem Mahmoud El-Sherif, Mohamed Said El-Shorbagy, Mohamed Samy El-Hakimᶜ, Abd El Jawad Said Mohamed, Zakarya Mohamed Zakarya and Ahmed Hassan Amer Khadrawy. Role of adhesion molecules & IL 1β in peptic ulcer disease. Nat Sci 2017;15(7):17-24]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 3. doi:10.7537/marsnsj150717.03.

 

KeywordsRole; adhesion; molecule; IL 1β; peptic ulcer disease

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Relation between Perineal body Length and Lacerations at delivery

 

Mohammed M. Farahat, Mofeed Fawzy, Waleed El Sheikh, Mohammed S, Fouad, Mahmoud yousry

 

Department of Obstetrics and Gyneology, Faculty of Medicine, Al-Azhar University, Egypt.

Mahmoudyousry1987@yahoo.com

 

Abstract: Background To define normal perineal body length during labor and determine if a shortened perineal body is associated with perineal lacerations or operative vaginal delivery. Objectives: evaluate the effect of perineal stretching on perineal damage during vaginal delivery. Materials and Methods: Delivery will be carried out in lithotomy position and perineal measurements (to the nearest 0.5 cm) will be obtained on 3 different occasions for each parturient: the beginning of the active phase of labor (effacement of 80-100% and 3-4cm dilatation), during the second stage, with the vertex at the crowning position (before episiotomy will be performed, if at all), and 24 hours after delivery. Landmarks used for perineal measurement included perineal body length (the distance between the posterior fourchette and center of the anal orifice), and genital hiatus length (the distance between the middle of external urethral meatus and the fourchette), Perineal measurements will be obtained using a flexible measuring tape disinfected by betadine against the perineal tissue during measurement. For each patient, we will make a record for the following characteristics: maternal age, height, weight, gestational age, duration of first and second stage of labor, use of oxytocin, use of forceps or vaccum, epidural use, episiotomy use, and blood loss at delivery. Birth outcome data will be obtained and will include the infant's sex, weight, head circumference, Apgar score and mode of delivery, occiput position and use of instrumentation. Perineal outcome included the use of episiotomy, spontaneous extension, presence and degree of spontaneous lacerations, and anal damage. This will be assessed by an attending physician. Relation between perineal body length at second stage of labour, third stage and laceration against HC of fetus, dyspareunia and incontinence at 2, 4, 6 weeks after delivery. Results: According to the results the patients were categorized into two groups:-Group I: patients with perineal body length ≤ 3.5cm (N=16). Group II: patients with perineal body length >3.5cm (N=84). Another classification is done according to the perineal stretching into: Group of perineal stretching<150%:(N=94). Group of perinealstretching ≥ 150 %: (N=6 According to the follow up of patients three months after delivery they were classified into:- Episiotomy group (N=52): including patients to whom episiotomy was done. Non Episiotomy group (N=48): including patients with intact perineum, first, and second degree perinea tears. The incidence of perineal tear was statistically significant higher in the group of perineal stretching ≥150%thanthatisin the group of perineal stretching <150%. According to the follow up of patients three months after delivery, no difference was found in the incidence of stress urinary incontinence, dyspareunia, and perinealpainin then on-episioto my group and the episioto my group. The incidence of anal incontinence was 0%. No significant correlation was found between the perineal body length and body mass index, maternal weight, maternal height, duration of the first stage of labor, nor the duration of the second stage of labor. It was found that there was a significant positive correlation between perineal stretching and degree of perineal tear. It was found that there was a significant positive correlation between the length of episiotomy and the duration of 2nd stage of labor. Conclusion: A short perineum in a given patient should alert the obstetrician to the potential for complications related to perineal trauma from delivery.

[Mohammed M. Farahat, Mofeed Fawzy, Waleed El Sheikh, Mohammed S, Fouad, Mahmoud yousry. Relation between Perineal body Length and Lacerations at delivery. Nat Sci 2017;15(7):25-30]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 4. doi:10.7537/marsnsj150717.04.

 

Keywords: perineal tear, perineal body length, laceration at delivery, Post partum pain, dysparunia, urinary incontence, fecal incontence

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Antagonistic Effect of Some Antifungal Substances against Fungi Causing Rots of the Glassy Clover Snail Baits

 

Hend Sh. Ghareeb and Lokma, M. H. E.

 

Plant Protection Research Institute, Dokki, Giza, Egypt

hendshokry111111@gmail.com

 

Abstract: Mouldiness is one of the most common microbiological defects found in molluscicide baits. Total count of fungi which associated with metaldehyde, methomyl and salicylic acid baits was detected under laboratory and field conditions. The antagonistic effect of four common antibiotics (locasten, mycostatin, terbin and trosyd) was estimated against these fungi. Moreover, effect of antibiotics on the molluscicidal activity of baits against Monacha cartusiana snails was assessed under the laboratory and field conditions. Result showed that in the laboratory, Aspergillus flavus and Rhizopus stolonifer were the most predominant fungi on the tested and control baits. But Aspergillus niger and Fusarium subglutinans were appeared only on salicylic acid and metaldehyde baits, respectively. In the field, A. flavus and R. stolonifer were the two only fungi which associated with salicylic acid and metaldehyde baits, respectively. Regarding to antibiotics, the highest effect of locasten was showed against A. niger and R. stolonifer by MIC value 0.2%. While, the highest activity of mycostatin and terbin was recorded against R. stolonifer by MIC values 0.04 and 0.02%, respectively. The highest antifungal effect of trosyd was exhibited against R. stolonifer by MIC value 0.08%. About the effect of baits alone and at mixing with antibiotics against M. cartusiana snails, in the laboratory methomyl with terbin, methomyl with trosyd and methomyl with mycostatin were the most potent baits against snails. Under field conditions, mycostatin increased the molluscicidal activity of salicylic acid and methomyl baits against snails and it showed also a high ability for attract snails to baits. For this reason, this antibiotic considered a promising antifungal and attractive material can add to the different molluscicide baits for control land snails in the future studies.

[Hend Sh. Ghareeb and Lokma, M. H. E. Antagonistic Effect of Some Antifungal Substances against Fungi Causing Rots of the Glassy Clover Snail Baits. Nat Sci 2017;15(7):31-43]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 5. doi:10.7537/marsnsj150717.05.

 

Keywords: Mouldiness of baits, antifungal activity of antibiotics, control of M. cartusiana snails.

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Assessment of Prevalence of Stress Urinary In continnence during Pregnancy

 

Hazem Mohamed Sammour1, Amgad Al Said Abou-Gamrah1, Haitham Mohamed Sabaa1, Mohammed Nour Allah Abdel Monem Ibrahim2

 

1Department of Obstetrics and Gynecology, Ain Shams University, Cairo, Egypt

2Resident of Obstetrics and Gynecology, Damanhur Teaching Hospital, Damanhur, El Behera, Egypt

mailto:m_n_allah@hotmail.com

 

Abstract: Introduction and hypothesis the aim of the study was to investigate the prevalence of stress urinary incontinence during pregnancy and associated risk factors. Methods a cross sectional study of 498 women half of them in the first trimester and the other in the third trimester. Results the prevalence of stress urinary incontinence was 12.4% in the first trimester and increased to 20.4% in the third trimester. Previous history of incontinence during childhood, number of deliveries and method of delivery are the risk factors to develop stress urinary incontinence.

[Hazem Mohamed Sammour, Amgad Al Said Abou-Gamrah, Haitham Mohamed Sabaa, Mohammed Nour Allah Abdel Monem Ibrahim. Assessment of Prevalence of Stress Urinary Incontinnence during Pregnancy. Nat Sci 2017;15(7):44-51]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 6. doi:10.7537/marsnsj150717.06.

 

Key words: Stress urinary incontinence, risk factor, trimester, pregnancy

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Tumour Necrosis Factor and Sperm Nuclear DNA Integrity in Semen of Infertile Males

 

Ahmed Mohammed Abdel- Aal1, Ibrahim Mohamed Abdel Salam1 and Mohammed Ibrahim Aref2 and Mohammed Hassan Wahba1

 

1Dermatology, Venerology and Andrology Department; Faculty of Medicine (For Males), Al-Azhar University, Egypt

2Clinical Pathology, Department; Faculty of Medicine (For Males), Al-Azhar University, Egypt

Email: mwrealestate84@yahoo.com

 

Abstract: Background: TNF is a proinflamatory cytokine that has recently been blamed to cause male infertility. Pathologically high levels Sperm DNA fragmentation has emerged as a potential causative factor of reproductive failure as well as failure to conceive with intra-cytoplasmic sperm injection (icsi). Anti-sperm antibodies (ASA), varicocele (VC), and genital Infection with or without inflammation & leukocytospermia can cause male infertility directly or indirectly through pathologically increasing TNF. Aim of the work: This study aims to evaluate seminal levels of TNF-α in correlation with sperm parameters and sperm nuclear DNA integrity in infertile males. Methods: A Total of 80 male subjects with ages ranging from 25-50 years were included in this study. 40 infertile males compared with 40 healthy fertile males. Patient groups were subdivided into group (A) Varicocele, group (B) leukocytospermia, group (C) genital infection, and group (D) antisperm antibodies. All patients groups were subjected to the following. Seminal fluid TNF-α, COMET assay for sperm nuclear DNA fragmentation, seminal ASA. Lastly seminal analysis to detect sperm parameters, and seminal culture to detect genital infection. Results: TNF-α was increased in all patient groups and correlate significantly with defaults in sperm parameters and sperm nuclear DNA fragmentation. TNF-α were significantly increased and correlated with Varicocele grades genital infection and leukocytospermia. Although TNF-α was significantly increased in patients with antisperm antibody but not correlated. Discussion: TNF has direct role in infertility either through caspase activation and/or increasing both reactive oxygen species (ROS) and nitric oxide (NO).

[Ahmed Mohammed Abdel- Aal, Ibrahim Mohamed Abdel Salam and Mohammed Ibrahim Aref and Mohammed Hassan Wahba. Tumour Necrosis Factor and Sperm Nuclear DNA Integrity in Semen of Infertile Males. Nat Sci 2017;15(7):52-60]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 7. doi:10.7537/marsnsj150717.07.

 

Keywords: Tumour; Necrosis; Factor; Sperm; Nuclear; DNA; Male

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Effect of age on quality of semen parameters

 

Yahya Mohamed Hodeeb1; Ahmed Rashad Elshahed1; Heba Mohamed Abd El Galil2; Nabil Fathy Ismail3; Tamer Noamani Abd Al-fatah1

 

1Dermatology, Venerology and Andrology Department; Faculty of Medicine (For Males), Al-Azhar University, Egypt

2Community Medicine Department; Faculty of Medicine (For Girls), Al-Azhar University, Egypt

3Clinical Pathology Department; Faculty of Medicine (For Males), Al-Azhar University, Egypt

Tamerhegab40@gmail.com

 

Abstract: Background: Increased life expectancy, advanced age of marriage, various socio-economic factors and an overall change in role of women in society has led couples to start their family at a later age). Higher maternal and paternal age raises the question of fertility maintenance during the ageing process. Aim of the work: to determine the association between male age and semen quality (semen volume, concentration, motility, and morphology) in healthy men. Patients and methods: This is a cross sectional comparative study that consisted of a convenience sample of 452 male volunteers. The patients were selected from (Kanater men's prison). The study was carried out on apparently healthy men (volunteers) (aged 20 – 60 years) with no history of infertility or reproductive problems. They were selected during the period from June 2016 to march 2017. All were submitted to full history taking, clinical examination with stress on genital examination and semen analysis. Results: All men enrolled in this present study was grouped according to age to four age groups as follow; 20-30 (33.3%), 30-40 (38.5%), 40-50 (16.8%) and ≥ 50 (11.5%) group. The highest number of men 174 present in age group 30-39 years represent (38.5%) of all men enrolled in this study while The lowest number of men 52 present in age group ≥50 years represent (11.5%) of all men enrolled in this study. Semen quality varied as regard age groups; It was found that the highest mean of seminal volume 3.01(+0.8 SD) ml was recorded among men of age group 20-30 years and the lowest was among men of age group ≥ 50 years with mean 1.6 (+0.9 SD) ml. As regard sperm concentration it was highest among those of age group 20-30 years with mean 92(+24 SD) million/ml and the lowest was among men of age group ≥ 50 years with mean 79.8(+13 SD) million/ml. Men of age group 20-30 years have the highest mean of total sperm count, progressive motility, non-progressive motility, total sperm motility and normal sperm morphology:281.6 (+114.5 SD) million,33.3(+6.8 SD) %, 17.9(+4.5 SD) %, 145 (+67.6 SD) million and 32.7 (+3.4 SD) % respectively, Followed by those of age group 30-40 years and age group 40-50 years. While the lowest mean of total sperm count, progressive motility, non-progressive motility, total sperm motility and normal sperm morphology were recorded among those of age group ≥ 50 years, they were as follows; 129 (+42.5 SD) million, 17.7(+8.1 SD) %, 10.8(+4 SD) %, 38.8 (+21 SD) million and 6.8 (+2.1 SD) % respectively. All these differences were statistically significant. Conclusion: significant age-related decreases in semen quality were observed, most notably for semen volume and sperm motility. Because semen quality is a proxy for fertility, these data suggest that men may become progressively less fertile as they growth older.

[Yahya Mohamed Hodeeb; Ahmed Rashad Elshahed; Heba Mohamed Abd El Galil; Nabil Fathy Ismail; Tamer Noamani Abd Al-fatah. Effect of age on quality of semen parameters Relation between Perineal body Length and Lacerations at delivery. Nat Sci 2017;15(7):61-66]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 8. doi:10.7537/marsnsj150717.08.

 

Keywords: ageing, semen analysis.

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Effect of inguinal hernioplasty on testicular function in young adults

 

Mohamed Mostafa Balbola; Naga hmohamed; Tarek emran; Ahmed Eldeek; Mohammad Naroz

 

General surgery Department, Faculty of Medicine, Al-Azhar University, Egypt

dr_naroz@yahoo.com

 

Abstract: Background: To assess theeffect of hernioplasty on testicular function regarding testicular blood flow, volume, and sperm function in young adults. Design: prospective randomized study. Patients and methods: This study was conducted on 100 patients of different ages ranging from 20-40 years old complaining from inguinal hernias were examined and admitted to the department of surgery, Al Azhar university hospital (New Damitta), preoperative semen analysis and duplex scan on testicular vessels and testicular size, followed by semen analysis, duplex scan 3, 6 monthes after surgical hernia repair. Results: No differences in testicular volume or in peak systolic velocity were observed between the hernia and healthy sides of the body (P > 0.05). Preoperatively, there was a significantly higher end diastolic velocity (P < 0.04) and resistive index (P < 0.001) on the hernia side compared with the normal side; these elevations returned to normal postoperatively. By the end of the study, the mean total sexual score and the number of patients with enhanced total score had showed further clinical progress, The total generic quality-of-life score, general health perception and physical function, vitality, and social domains were statistically recovered at 3 months postoperative (P < 0.05), with further improvement in total score at 6 months. Conclusion: No alteration in testicular volume and arterial flow over a six-month period observed among patients who underwent surgical correction for inguinal hernia using a polypropylene prosthesis whether Lichtenstein tension free technique (anterior) or preperitoneal technique (posterior) used.

[Mohamed Mostafa Balbola; Nagahmohamed; Tarekemran; Ahmed Eldeek; Mohammad Naroz. Effect of inguinal hernioplasty on testicular function in young adults. Nat Sci 2017;15(7):67-72]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 9. doi:10.7537/marsnsj150717.09.

 

Keywords: Testicular perfusion, Hernioplasty, Sexual function, Lichtenstein technique.

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Epidemiology of Mode of Labour in Suez General Hospital

 

Hosam El Din Hussein Kamel1; Mohamed Mohamed Ibrahim Gebril1; Hesham Fekry Ahmed Abou Senna1; Khaled Abd El-Maboud Mohamed Tawfik2

 

1Obstetrics & Gynecology Department, Faculty of Medicine, Al-Azhar University, Egypt.

2Resident Doctor of Obstetrics & Gynecology, Suez General Hospital, Egypt.

Jacsparo2010@yahoo.com

 

Abstract: Cesarean section (CS) rates have been increasing world wide, raising the question of the appropriateness of the selection of cases for the procedure. The World Health Organization (WHO) states that no region in the world is justified in having a cesarean rate greater than 10 to 15 percent, The Egypt Demographic Health Survey (EDHS) in 2014 revealed that 52% of deliveries in Egypt were by CS from survey in the previous six years before 2014, So the present work aimed to study the current trend in obstetric practice towards route of delivery whether vaginal or abdominal and rate of cesarean section in governmental hospitals nowadays. To accomplish this mission, a prospective study collected data from patient records in the period from 1-7-2015 to 31-12-2015 from patients attending labour ward at Suez general hospital for delivery to assess the modes of delivery and their relation to the feto-maternal mortality and morbidity. The study revealed that, the total CS rate was 33.0% compared to 66.2% for vaginal delivery and 0.8% for Vaginal Birth After CS (VBAC) and the rate of the primary C.S was 29.8%, the most common indication among CSs was repeated elective C.S (50.8%), the second common indication was failure to progress (13%), also there was increased CS rate with mal-presentations, postdates (especially with unfavorable cervix for induction), and abnormal Cardiotocography, There was a higher frequency of maternal admission to ICU and maternal death with CS mostly due to obstetric and/or medical complications rather than a complication from the procedure itself. There is a higher frequency of fetal morbidity and mortality with CS, most of them due to respiratory complications and congenital malformations.

[Hosam El Din Hussein Kamel; Mohamed Mohamed Ibrahim Gebril; Hesham Fekry Ahmed Abou Senna and Khaled Abd El-Maboud Mohamed Tawfik. Epidemiology of Mode of Labour in Suez General Hospital. Nat Sci 2017;15(7):73-78]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 10. doi:10.7537/marsnsj150717.10.

 

Keywords: Mode of delivery, Cesarean section, Suez, How to reduce caesarean section rate?

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Comparative study between Single Port Laparoscopic Cholecystectomy (SPLC) and Traditional Laparoscopic Cholecystectomy (TLC)

 

Ahmed Mohammed Ahmed Ata1, Ibrahim Mahmoud Elsayaad1, Gamal El-Sayed Al-Maadawy2

 

1General surgery Department, Faculty of Medicine, Al-Azhar University, Damietta, Egypt

2Pediatric Unit, Faculty of Medicine, Al-Azhar University, Damietta, Egypt

Halaahmedata@gmail.com

 

Abstract: Background: Laparoscopic Cholecystectomy (LC) provides a safe and effective treatment for most patients with symptomatic gallstones and has become the treatment of choice for many patients and with development of the traditional technique and with seeking of the surgeons and patients to less scaring, the SPLC developed. Objective: comparison between single port and traditional multiple ports LC and explain if single port can be an alternative to multi-port or not. Patients and methods: Forty patients presented to the outpatient clinic during the duration between January 2015 and January 2017. These patients were randomly divided into two equal groups: group (A) was subjected to TLC, and group (B) was subjected to SPLC. All patients were submitted to preoperative assessment (history taking, physical examination, laboratory investigations, imaging studies, cardio-pulmonary assessment), abdominal ultrasonography (U/S), magnetic resonance cholangiopancreatography (MRCP) if needed and preoperative quality of life assessment. Patient education about the Gall Bladder (GB) function and several ways for removal was provided. All patients of the two groups were informed about the advantages and disadvantages of the procedure that will be dine for him/her and consented to be involved in this study. The patient signed written consent for the procedure to be performed for him/her. Results: Patients were followed up for overall outcome and postoperative complications. The operative time in TLC was (45.37.1) and in SPLC was (61.46.9) with P value P<0.05 which was statistically significant, no cases required conversion with TLC, 4 cases with a percentage of 20% with SPLC with P value= 0.037 which was statistically significant, Cosmetic appearance with TLC1 month post-operative satisfied (7.5 3.4) patients and after 6 month satisfied(8.6 2.1) patients and with SPLC 1 month post-operative satisfied (8.84.1) patients and after 6 month satisfied(9.1 3.6) patients with p value <0.05 which was statistically significant, length of hospital stay after TLC (53.1 7.27) and after SPLC (68.411.5) with p value <0.05. Conclusion: SPLC appeared to be as safe and effective as TLC.SPLC is feasible and safe for treatment of uncomplicated GB disease. SPLC is a promising alternate method to TLC.

[Ahmed Mohammed Ahmed Ata, Ibrahim Mahmoud Elsayaad, Gamal El-Sayed Al-Maadawy. Comparative study between Single Port Laparoscopic Cholecystectomy (SPLC) and Traditional Laparoscopic Cholecystectomy(TLC). Nat Sci 2017;15(7):79-89]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 11. doi:10.7537/marsnsj150717.11.

 

Keywords: Traditional Laparoscopic Cholecystectomy, SPLC, GB stones diagnosis and treatment

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Evaluation of Bleomycin Injection in Treatment of Infantile Haemangiomas

 

Mohamed Ahmed Abd El-Maaboud Abo omar; Sayed Ahmed El-hady Abd El-Monem and Ayman Ameen Mohy El-Din

 

General surgery Department, Faculty of Medicine, Al-Azhar University, Damietta, Egypt.

Myjado37@gmail.com

 

Abstract: Background: to assess the efficacy of bleomycin injection as a one of different modalities in treatment of infantile haemangiomas. Design: Prospective study. Patients and methods: This study was done on 40 patients (26 females, 14 males) with infantile haemangiomas, recruited prospectively from the pediatric surgery outpatient clinic at Al-Azhar university hospital (New Damietta) during the period from July 2016 till December2016 and all patients were observed for six months. Results: After a minimum follow-up of 6 months, 6 patients (30%) showed complete resolution of their lesions after 2-3 injections with marked colour fading and great parental satisfaction. The remaining 14 patients (70%) need more injections (4-6 injections) to be completely improved. Conclusion: Intraregional injection of bleomycin is an easy, safe, and effective therapeutic modality in cutaneous haemangiomas.

[Mohamed Ahmed Abd El-Maaboud Abo omar; Sayed Ahmed El-hady Abd El-Monem and Ayman Ameen Mohy El-Din. Evaluation of Bleomycin Injection in Treatment of Infantile Haemangiomas. Nat Sci 2017;15(7):90-94]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 12. doi:10.7537/marsnsj150717.12.

 

Keywords: haemangiomas, complications, intralesional bleomycin injection

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Susceptibility of Egyptian native breed chickens (Gmisa) to experimental infection with highly pathogenic avian influenza virus (H5N1)

 

Saleh M.M1, Selim A2, Shahera A.A. 3, El Shahidy M.S.3, ElTrabilli M.M3

 

1Animal Health Research Institute, Mansura, Dakahlia, Egypt

2National Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Dokki, Giza, Egypt

3 Department of Virology, Faculty of Veterinary Medicine, Suez-Canal University, Egypt.

mostafasaleh2017@hotmail.com; zanatyali@yahoo.com

 

Abstract: Highly Pathogenic Avian Influenza (HPAI) H5N1 virus is an ongoing public health and socio-economic challenge, particularly in Egypt. H5N1 is now endemic in poultry in many countries, and represents a major pandemic threat and have caused multiple human infections. The main objective of this work to highlights on the susceptibility of Egyptian Gimazachickens to experimental infection with H5N1 avian influenza virus and to get a comprehensive view of Gimaza adaptation to H5N1 virus. Nucleotide and amino acid alignment of HA gene after serial passage in Gimaza chickens revealed no changes in cleavage site and receptor binding site. Only few amino acid substitutions in some antigenic sites were recorded. Gimaza breed appeared to be more sensitive to H5N1 Giza strain as evaluated by the MDT and virus shedding.

[Saleh M.M, Selim A., Shahera A.A., El Shahidy M.S. and ElTrabilli M.M. Susceptibility of Egyptian native breed chickens (Gmisa) to experimental infection with highly pathogenic avian influenza virus (H5N1). Nat Sci 2017;15(7):95-104]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 13. doi:10.7537/marsnsj150717.13.

 

Keywords: Native, Gimaza, HPAI, H5N1, Genetic Resistance, rRT-PCR

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Surgical Options for Treatment of Posterior Fossa Tumors with Hydrocephalus

 

Mohamed Mahmoud Abohashima; Ahmed Mohamed Hasan Salem; Magdy Asaad El-Hawary

 

Neurosurgery department, Faculty of Medicine, Al-azhar University, Egypt

Abohashima_1987a@yahoo.com

 

Abstract: Background: A brain tumor is one of the most devastating forms of human illness, especially when occurring in the posterior fossa. Brainstem compression, herniation, and death are all risks in tumors which occur in this critical location. Aim of the work: The aim of this work is to review clinical presentation, pathology, methods of investigations, operative techniques, complications of management of posterior fossa tumors and eventually prognosis. Also, this study aims at comparing the results of different types of management in order to establish the optimum way for management of posterior fossa tumors. Subjects and Methods: The admission, progress and outcome data of 24 patients with of posterior fossa tumors with hydrocephalus are collected in this series. Patients were grouped into 2 groups. The first group will be managed by direct surgical excision of the tumor and the second group will be managed by ventriculo-peritoneal (V-P) shunting, EVD or ETV prior to definitive surgery followed by direct tumor attack. Results: briefly in our study: 6 patients (60%) were completely cured of hydrocephalus without recurrence after total tumor excision in group (1) and 9 patients (64%) were completely cured of hydrocephalus without recurrence after total tumor excision in group(2). Only 3 patients 42% out of the 7 patients having external ventricular drainage in group 2 needed permanent CSF diversion. Recommendation: Decision of CSF diversion in posterior fossa tumor should be individualized according to patient condition and is not aroutine.

[Mohamed Mahmoud Abohashima; Ahmed Mohamed Hasan Salem; Magdy Asaad El-Hawary. Surgical Options for Treatment of Posterior Fossa Tumors with Hydrocephalus. Nat Sci 2017;15(7):105-110]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 14. doi:10.7537/marsnsj150717.14.

 

Keywords: Surgical Option; Treatment; Posterior Fossa Tumor; Hydrocephalus

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Diagnostic Value of Ultrasonography and Magnetic Resonance Imaging in Pregnant Women at Risk For Placenta Accreta

 

Yehia A. Wafa1, Ahmed Samy Soliman1, Mostafa Fadel Sonpol2, Ahmed Osama Abd Almotaal1, Mohamed Abdel-Aziz Elzayat1, Mohamed Ibrahim Abd Al Kader Elbarbary1

 

1Obstetrics and Gynecology Department, Faculty of Medicine, Al-Azhar University, Egypt

2 Radiology Department, Faculty of Medicine, Al-Azhar University, Egypt

dr.mohamed.elzayat@hotmail.com

 

Abstract: Background: Placenta accreta (PA) encompasses various types of abnormal placentation in which chorionic villi attach directly to or invade the myometrium. PA is a significant cause of maternal morbidity and mortality and is now the most common reason for emergent postpartum hysterectomy. Objectives: To evaluate whether ultrasonography and magnetic resonance imaging can detect placentaaccreta reliably in at-risk patients. Design: A prospective observational study. Setting: AL-Hussein University teaching hospital. Patients: 50 pregnant women with abnormal placentation and previous uterine surgery were collected after meeting the inclusion criteria depending on gray-scale sonographic findings which suggested placenta accreta. Ultrasonography (US) and resonance imaging (MRI) findings were classified as positive and negative according to presence or absence of imaging criteria of placenta accreta. Cases attended the antenatal clinic of Obstetrics and Gynecology Department of AL-Hussein University hospital and investigated in Department of Radiodiagnosis during the period from January 2016 to January 2017. Results: From 50 patients with placenta previa only 18 patients were confirmed to have placenta accreta after delivery based on pathological findings and examination by ultrasound and MRI, all cases have placenta previa on top of cesarean deliveries 37 of them have placenta previa anterior,13of them have placenta previa posterior, 43 of cases have placenta previa centralis (complete, incomplete) and 7 of cases have placenta marginalis; Accreta cases were more detected in placenta previa centralis. Conclusion: The result of the present study shows that the use of prenatal transabdominal gray –scale ultrasonography can detect or suspect placental invasion.

[Yehia A. Wafa, Ahmed Samy Soliman, Mostafa Fadel Sonpol, Ahmed Osama Abd Almotaal, Mohamed Abdel-Aziz Elzayat, Mohamed Ibrahim Abd Al Kader Elbarbary. Diagnostic Value of Ultrasonography and Magnetic Resonance Imaging in Pregnant Women at Risk For Placenta Accreta. Nat Sci 2017;15(7):111-116]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 15. doi:10.7537/marsnsj150717.15.

 

Keywords: Ultrasound, MRI, placenta accreta

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Environmental Impacts of Metal Pollution Sources on Rosetta Branch Water Quality

 

Ibrahim, A. M.1, Kamel, S. A.1, OMAR, A. S.2 and Madkour, H. A.2

 

1 Geology Department, Faculty of Science, Al Azhar University, Cairo, Egypt

2 National Institute of Oceanography, (Hurghada–Red Sea Branch), Egypt

Sherif_geology@yahoo.com

 

Abstract: The purpose of the present paper is to study the environmental impacts of trace elements pollution source son, Egypt Rosetta branch, water quality. Water quality studies on Rosetta Branch were performed through the analyses of twenty three geographical station water samples collected periodically through February and June months to represent the two seasons of year 2012. Water Quality along Rosetta Branch was determined. The worth case was found along El–Rahawy drain at the area between Abu Rawash City and Nekla Village. Correlation Matrix, chemical parameter characteristics, was computed and the result of correlation matrix for the data shows some clear hydro-chemical relationships can be readily inferred.

[Ibrahim, A. M., Kamel, S. A., OMAR, A. S. and Madkour, H. A.. Environmental Impacts of Metal Pollution Sources on Rosetta Branch Water Quality. Nat Sci 2017;15(7):117-123]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 16. doi:10.7537/marsnsj150717.16.

 

Keyword: Pollution, Sources Rosetta, Branch

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Association of HCV infection and diabetes mellitus type 2 in Damietta

 

Mohammed I. Aref, Mekky A. Ali, Mahmoud F. Salem and Mohammed E. Ahmed

 

Department of Clinical Pathology, Faculty of Medicine, Al-Azhar University, Egypt.

ayam02906@gmail.com

 

Abstract: Background: Hepatitis C virus (HCV) infection and diabetes mellitus are the major public health challenges with increasing morbidity and mortality disease burden. Several studies reported that HCV infection may also contribute to the development of diabetes mellitus. Objective: to clarify the presence of any possible relationship between HCV and type 2 Diabetes mellitus and the prevalence of diabetes mellitus in HCV seropositive patients in Damietta. Subjects and Methods: This is a case control study done on 70 HCV positive patients as a case group who were attended to Damietta University Hospital and 30 healthy individuals as a control group, during the period from May 2016 to April 2017. An informed consent was taken from all subjects participating in this study. All subjects included in this study were subjected to: Full history taking, Clinical examination and Laboratory investigation in the form of (complete blood picture, liver enzymes, S.albumin, T.bilirubin, fasting & 2hpp blood glucose, fasting plasma insulin and screening for HCV and HBV). Results: The results of present study showed no statistical significant differences between case and control groups as regard to age, sex and total leukocytic count. while there were statistical significant differences between case and control groups as regard to fasting plasma insulin, fasting plasma glucose,2hpp plasma glucose, ALT, AST, albumin, bilirubin, cholesterol and triglycerides. Conclusions: Many epidemiological studies have shown an association between T2DM and CHC. The processes through which HCV is associated with DM seem to involve direct viral effects, IR, proinflammatory cytokines, chemokines, suppressors of cytokine signalling, and other immune-mediated mechanisms.

[Mohammed I. Aref, Mekky A. Ali, Mahmoud F. Salem and Mohammed E. Ahmed. Association of HCV infection and diabetes mellitus type 2 in Damietta. Nat Sci 2017;15(7):124-127]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 17. doi:10.7537/marsnsj150717.17.

 

Keywords: Hepatitis C infection, Type 2 Diabetes mellitus, Insulin resistance

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Maternal mortality associated with repeated Cesarean Section

 

Abdel Sattar Farhan, MD, Hossam Eldin Hussin, MD, and and Motaz Talaat, M.B., B.CH.

 

Obstetrics and Genecology Department, Faculty of Medicine. Al-Azhar University, Cairo, Egypt

motaz.elghnam@kasralainy.edu.eg

 

Abstract: Hemorrhage is the main cause of mortalities in most of developing countries including Egypt followed by VTE, while sepsis usually comes in the 3rd place. On the other side, in developed countries, VTE is the main cause of maternal deaths followed by hemorrhage and sepsis. Complications of anathesia and amniotic fluid embolism have a minor share in the causes of maternal mortalities with repeated CS in both developing and developed countries.

[Abdel Sattar Farhan, Hossam Eldin Hussin, and and Motaz Talaat. Maternal mortality associated with repeated Cesarean Section. Nat Sci 2017;15(7):128-130]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 18. doi:10.7537/marsnsj150717.18.

 

Keyword: Mortality, Cesarean Section.

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Manual Placental Removal versus Cord Traction for Placental Delivery at Caesarean Section in Correlation to Blood Loss

 

Mohamed Samir Foad M.D., Tamer Fares Oof M.D., and Emad Abd El-Tawab

 

Obstetrics & Gynecology Department, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

emadabdoabdo@gmail.com

 

Abstract: Background: Excessive bleeding is one of the major threats to women at childbirth. Blood loss during caesarean section is usually underestimated. Objective: The objective of this study was to compare the effects of manual extraction of placenta versus spontaneous delivery combined with cord traction on blood loss during elective caesarean section. Subjects and Methods: This is a comparative randomized controlled study was carried out at El-Hussein University Hospital OB/GYN Department and El Sahel Teaching Hospital OB/GYN Department from Feb. 2015 to December 2015. Eighty women with term gestation scheduled for elective lower segment caesarean section were randomized into 2 groups, Group I (manual removal of placenta) (n=40) and Group II (spontaneous placental delivery with cord traction) (n=40) and their intraoperative and postoperative outcomes were studied and were statistically compared. Results: There was a significantly higher estimated intraoperative blood loss in Group I when compared to Group II [505.08 150.14 ml vs. 434.09178.52 ml, respectively, p<0.001]. There were no statistically significant differences between women of both groups concerning postoperative hemoglobin and postoperative hemoglobin drop. Postoperative hematocrit [30.91 2.49 vs. 32.6 3.12, respectively, p=0.001] and postoperative hematocrit drop [3.06 1.04 vs. 2.02 1.47, respectively, p=0.003] were, however, significantly lower in Group I when compared to women in Group II. There was a significantly shorter mean duration of placental delivery [0.28 0.15 min vs. 3.65 2.75 min, respectively, p<0.001] in Group I, but the mean duration of the operation was similar. Conclusion: Our Study showed that Spontaneous delivery of the placenta combined with cord traction as compared to manual removal significantly reduces the blood loss without increasing the operating time.

[Mohamed Samir Foad, Tamer Fares Oof, and Emad Abd El-Tawab. Manual Placental Removal versus Cord Traction for Placental Delivery at Caesarean Section in Correlation to Blood Loss. Nat Sci 2017;15(7):131-136]. ISSN 1545-0740 (print); ISSN 2375-7167 (online). http://www.sciencepub.net/nature. 19. doi:10.7537/marsnsj150717.19.

 

Keywords: Caesarean section; Placenta; Placental delivery; Blood loss; Hemoglobin.

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The manuscripts in this issue are presented as online first for peer-review starting from May 4, 2017.

 All comments are welcome: editor@sciencepub.net

For back issues of the Nature and Science, click here.

Emails: editor@sciencepub.net; sciencepub@gmail.com; naturesciencej@gmail.com

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2017 Marsland Press