Volume 3 - Issue 2 (Cumulated No. 20), February 1, 2011, ISSN 1553-9865
Cover Page, Introduction, Contents, Call for Papers, Research 0302
Welcome to send your manuscript(s) to: firstname.lastname@example.org
Titles / Authors
Evaluation Of Antifungal Effects Of
Extracts Of Allium Sativum And Nicotiana
Tobacum Against Soft Rot Of Yam (Dioscorea Alata).
Ijato James Yeni
DEPARTMENT OF PLANT SCIENCE, FACULTY OF SCIENCE, UNIVERSITY OF
ADO-EKITI P.M.B 5363, EKITI STATE, NIGERIA.
The antifungal effects of Allium sativum (rhizome)
and Nicotiana tobacum (leaf) extracts on rot
causing organisms on yam: Aspergillus
Fusarium oxysporum, Rhizopus stolonifer,
Botryodiplodia theobromae, Aspergillus
flavus and Fusarium solani. Treatment with
aqueous and ethanolic extracts of the test plants significantly
reduced the radical growth of the pathogens in vitro. Value 76.66% inhibition of Botryodiplodia theobromae
was obtained using 80% aqueous extract of Allium
sativum, 60% inhibition of Fusarium oxysporum was
obtained using 80% aqueous of Nicotiana tobacum,
86.66% inhibition of Botryodiplodia theobromae was
obtained using 30% ethanol on Allium sativum and
60.5% inhibition of Aspergillus niger was obtained
using 25% ethanol to extract 70% inhibition of Fusarium
solani was obtained using 30% ethanol to extract on N.
tabacum both the aqueous and the ethanolic extract of the
test plants were found to be more active as bio-killer on yam
James Yeni. Evaluation Of Antifungal Effects Of Extracts Of
Allium Sativum And Nicotiana Tobacum
Against Soft Rot Of Yam (Dioscorea Alata).
Researcher. 2011;3(2):1-5]. (ISSN: 1553-9865).
Allium sativum, yam, Nicotiana tobacum, plant
extract, rot organisms
Evaluation of Acoustic Parameters of Halides of
Alkali Metals and Ammonium in Aqueous and Aqueous Dextran Solutions at 298.15 K
Moharatha Dharitri1, Talukdar Malabika2,*,
Roy Gauri Shankar3, Dash Upendra Nath2
Department of Physics, N M Institute of
Engineering & Technology,
Bhubaneswar 751 019, Odisha, India
Department of Chemistry, I T E R,
Siksha ‘O’Anusandhan University,
Bhubaneswar 751 030, Odisha,India
Department of Physics,
Government College, Bhawanipatana,
The acoustic behavior of halides of alkali metals and ammonium
in aqueous and aqueous dextran solutions has been studied at
298.15 K. The structural arrangement of molecules of the solvent
has been discussed with reference to the electrostatic field of
ion in the solution. The qualitative intermolecular elastics
forces between the solute and solvent molecules are explained in
terms of compressibility.
[Moharatha Dharitri, Talukdar Malabika, Roy Gauri Shankar, Dash
Upendra Nath. Evaluation of Acoustic Parameters of Halides of
Alkali Metals and Ammonium in Aqueous and Aqueous Dextran
Solutions at 298.15K. Researcher. 2011;3(2):6-12]. (ISSN:
aqueous dextran solutions; alkali metal halides; apparent molar
volumes; isentropic compressibility
A Literature Review on the Log Export Ban Policy in Developing
Countries: From the Perspective of Environmental Economics
Klarizze PUZON, Arip MUTTAQIEN, Xingzhuo SONG and Dzung NGUYEN*
Corresponding Author’s Email
*Master in Economics Students,
Toulouse School of Economics, France.
The log export ban (LEB) policy, considered as the most extreme
form of log export taxation, was formulated to conserve forest
area and trigger growth. However, its effectiveness in achieving
the twin goals of economic efficiency and environmental
conservation has been widely debated. In this paper, the
efficacy of the log export ban policy is reviewed. Using
empirical evidence from Indonesia and Costa Rica, the opposite
sides of the debate (i.e. the effects of the implementation
versus the removal of the LEB) are analyzed. Lastly, alternative
policies, e.g. carbon payment schemes, are also briefly
PUZON, Arip MUTTAQIEN, Xingzhuo SONG and Dzung NGUYEN.
A Literature Review on the Log Export Ban Policy in Developing
Countries: From the Perspective of Environmental Economics.
Researcher. 2011;3(2):13-20]. (ISSN: 1553-9865).
Literature Review; Log Export; Ban Policy; Developing Country;
rations supplemented with fibrolytic enzyme on dairy cows
performance 2- In situ ruminal degradability of rations
containing different roughages at two concentrate to roughage
M I Bassiouni1,
H M A Gaafar2, M S Saleh1, A M A Mohi
El-Din2 and M A H Elshora2
1- Department of
Animal Production, Faculty of Agriculture, Kafrelsheikh
Production Research Institute, Agricultural Research Center,
Dokki, Giza, Egypt.
was conducted to study the effect of fibrolytic enzymes
supplementation on In Situ degradability of DM, CP and CF
of different rations consisted of concentrate feed mixture (CFM)
+ berseem hay (BH), dried sugar beet tops (DSBT), corn silage
(CS), rice straw (RS) or wheat straw (WS) in different ratios
60:40 or 40:60. The fibrolytic enzyme (fibrozyme) was added to
the ground rations at the levels of 0, 1 and 1.5 g/kg DM diluted
with distilled water (1:10 w/v) and sprayed with 10 ml per kg of
ground feedstuffs overnight and samples incubated in canulated
multiparous Friesian cows for 2, 4, 8, 16, 24, 48 and 72 hours.
Rations contained DSBT showed the highest values of in
situ DM, CP and CF disappearance followed by rations
contained BH, while rations contained RS or WS had the lowest
values (P<0.05). The percentages of in situ DM, CP and CF
disappearance for rations contained 60% concentrate: 40%
roughage was higher than rations contained 40% concentrate: 60%
roughage for different feedstuffs (P<0.05). Added fibrolytic
enzyme at the level of 1g/kg DM showed the highest DM and CF
disappearance in DSBT rations and CP disappearance in BH and
DSBT rations, while, the level of 1.5 g/kg showed the highest DM
and CF disappearance in BH, CS, RS and WS rations and CP
disappearance in CS, RS and WS rations (P<0.05). Rations
contained DSBT showed the highest rapid degradable fraction (a)
for DM, CP and CF, rations contained BH showed the highest
potential degradable fraction (b), rations contained CS had the
highest degradation rate (c), while, rations contained RS or WS
had the highest undegradable fraction (u) (P<0.05). The rapid
degradable fraction (a), the potential degradable fraction (b)
and the degradation rate (c) were higher, the undegradable
fraction (u) was lower for rations contained 60% concentrate:
40% roughage compared with those contained 40% concentrate: 60%
roughage for different feedstuffs (P<0.050. Moreover, rations
contained DSBT showed the highest outflow rate of degradable DM
at 2, 5 and 8%/ hour from the rumen and increased with
increasing concentrate level (P<0.05). The highest rapid and
potential degradable fractions, degradation rate and the outflow
rate at 2, 5 and 8%/ hour from the rumen and the lowest
undegradable fraction detected with added fibrozyme at level of
1g/kg for of DM and CF in DSBT rations and CP in BH and DSBT
rations and at level of 1.5 g/kg for DM and CF in BH, CS, RS and
WS rations and CP in CS, RS and WS rations (P<0.05).
[M I Bassiouni, H M
A Gaafar, M S Saleh, A M A Mohi El-Din and M A H Elshora.
Evaluation of rations supplemented with fibrolytic enzyme on
dairy cows performance 2- In situ ruminal degradability
of rations containing different roughages at two concentrate to
Researcher. 2011;3(2):21-33]. (ISSN: 1553-9865).
different roughages, concentrate: roughage ratio, fibrolytic
enzyme, in situ disappearance
on EctC gene (Ectoine) in some halophilic Bacterial Isolates.
M. K. Nada, 3M. H. Refaat, 3M. S.
M. Hassan and 3Abd El Kader, M.M.
Agricultural Genetic Engineering Research Institute (AGERI),
ARC, Giza, Egypt.
Faculty of Biotechnology, October University for Modern Sciences
and Arts (MSA).
of Genetics, Fac. of Agriculture, Benha University, Qalubia,
The ability of
microorganism to adapt the changes in the osmolality of
the external milieu is of fundamental importance for
growth and survival, and thus prokaryotic cells have
evolved a number of osmoadaptative mechanisms to cope
with elevated osmolality. One hundred bacterial
isolates were isolated from soil from Egypt and screened for
salt tolerance. The best four isolates were identified by
manual and API 20E system methods. Identification of bacterial
isolates showed that strains were Pseudomonas mallei,
Halococcus salifodinae, Pseudomonas flourecens, Pseudomonas
were designed for screening the bacterial isolates about the
EctC gene from octoine operon. The positive result was with
bacterial isolate Pseudomonas mallei. The length of
observed fragment was between 300-400 bp. SDS-PAGE analysis of
the four isolates revealed that the protein profile of the six
isolates were different from each other in their banding pattern
at different concentrations of NaCl (0.0 ppm,40.000 ppm and
58.500 ppm) respectively.
M. K. Nada, M. H. Refaat, M. S.
Abdel-Sabour, A. M. Hassan and Abd El Kader, M.M. Molecular
Studies on EctC gene (Ectoine) in some halophilic Bacterial
Isolates. Researcher. 2011;3(2):34-42]. (ISSN: 1553-9865).
Eco-Epidemiologic Aspects Of Mannheimia Haemolytica In
H.A. Kaoud1, A.R. El-Dahshan, Manal.M. Zaki1,
1 Shaaima1 .A. Nasr1
of Veterinary Hygiene, Environmental Pollution and Management,
Faculty of Veterinary Medicine, Cairo University, Giza 11221,
aim of this article was a trial to declare of the ecology of
Mannheimia haemolytica (P. haemolytica) among farm
animals in Egypt through the following :( 1) Checking up the
presumptive role of some environmental components in the
indirect transmission of the infection. (2) Investigating
survival and viability of the organism under simulated
environmental conditions. Nasal swabs were collected from
animals showed respiratory manifestations (cattle, buffaloes,
sheep and goats) in some farms in different Govemorates of
Egypt. Soil and Air samples from animal houses were also
obtained (A total of 435 samples).Results pointed out that; 27
isolates were recorded from 265 (10.16%) nasal swabs of herds
manifested respiratory sings (6.37% of animals showed
respiratory sings). 17 isolates were recorded from 100 examined
air samples (17%).And 4 isolates were recorded from 70 examined
soil samples (5.70%). There was a correlation between
Mannheimia. haemolytica isolation from the nasal cavities
and the dust content of the air (r =0.72) but it is not
significant (P < 0.05). In the same time, there was a
highly significant correlation between dust in the air and the
respiratory manifestations affecting the animals (r = 0.82,
(P< 0.05). It seems possible to conclude that the organism
is not capable of surviving outside the animal's body for long
time. M. haemolytica survived relatively longer in faeces
than in tap-water under different incubation temperatures. We
failed to isolate the other trehalose-negative species were
found representing the genus (Mannheimia) with five
species (M glucosida, M granulomatis, M
ruminalis, and M varigena).
Kaoud, A.R. El-Dahshan, Manal. M. Zaki, Shaaima. A. Nasr.
Eco-Epidemiologic Aspects Of Mannheimia Haemolytica In
Researcher. 2011;3(2):43-50]. (ISSN: 1553-9865).
- Mannheimia haemolytica
Improving Effect of
Dietary Oat Bran Supplementation on Oxidative Stress Induced By
Ola S Mohamed 1,Mostafa
M Said 2, Zeinab Y Ali 2,*, Hanan A Atia
1 and Heba S Mostafa 2
Biochemistry Department, Faculty of Pharmacy (girls), Al-Azhar
University, Cairo, Egypt
Department of Biochemistry, National Organization for Drug
Control and Research, Giza, Egypt.
Many epidemiological studies support the involvement of
oxidative stress in pathogenesis and progression of many
diseases such as hyperlipidemia and atherosclerosis. Oats (Avena
sativa, Linn.) are rich in antioxidants and have
cholesterol-reducing effect. This study aimed to evaluate the
total phenolic and antioxidant activity as well as the
prophylactic and curative effects of oat bran (2.70 g. kg-1
b.w. day-1) on oxidative stress induced by
hyperlipideamic diet comparing with simvastatin (3.6 g. kg-1
b.w.day-1) as reference agent. Rats fed on
hyperlipidemic diet supplemented with cholesterol, cholic acid
and thiouracil (CCT, 3:1:0.5) exhibited significant elevation in
hepatic antioxidant enzyme (SOD, CAT, GPx and GST) activities
and lipid peroxide (MDA), and a significant depletion in reduced
glutathione (GSH) content. Oat bran was able to maintain or
ameliorate these changes to nearly normal levels and reveals its
prophylactic and curative effects on oxidative stress associated
with hyperlipidemia. Oat bran has nearly similar potent
antioxidant effect as simvastatin. These beneficial effects
could be attributed to the antioxidant activities of bioactive
ingredients in oat bran. In conclusion, oat bran supplementation
exhibited a powerful antioxidant potential and, thus, reduce
incidence and prevent atherosclerosis through a reduction in
oxidative stress induced by hyperlipidemia in rats.
[Ola S Mohamed,
Mostafa M Said, Zeinab Y Ali, Hanan A Atia and Heba S Mostafa.
Improving Effect of Dietary Oat Bran Supplementation on
Oxidative Stress Induced By Hyperlipidemic Diet. Researcher.
2011;3(2):51-61]. (ISSN: 1553-9865).
Avena sativa; oat bran; total phenolics; antioxidant
activity; hyperlipidemia; atherosclerosis; oxidative stress;
Teaching Aids: A
Panacea for Effective Instructional Delivery in Biology
Iwu, Rosemary U.,
Ijioma, Blessing C, Onoja Abel .I, and Nzewuihe G.U
Biology, Alvan Ikoku Federal College of Education, Owerri. Imo
examines the role of teaching aids in effective instructional
delivery. Teaching aids are those relevant materials utilized by
the teacher during instructional process and they in turn affect
the behaviour of the learner. To effectively utilize
instructional materials in the teaching-learning process the
following principles and requirements should be adhered to in
the selection of teaching aids: Instructional tasks, target
audience attributes, the economy, dynamic variables and
environmental factors. The use of instructional materials should
follow the following guidelines: specification of objectives,
preparation and preview, maximal fit with instructional task,
environmental situations and measure of outcome. The problems
associated with the use of teaching aids include the following;
teachers professional knowledge and technical know-how, time,
finance and poor maintenance culture. In line with the above it
is recommended that teachers should endeavor to commit
themselves to effective use of teaching aids in all their
instructional delivery. A forum should be created where teachers
will endeavor to update their knowledge in the area of
educational technology in order to expose themselves to modern
technological apparatus and how to manipulate their functions
Rosemary U., Ijioma, Blessing C, Onoja Abel .I, and Nzewuihe G.U.
Teaching Aids: A Panacea for Effective Instructional Delivery in
Biology. Researcher. 2011;3(2):62-65]. (ISSN: 1553-9865).
Teaching Aids, Panacea, Instructional delivery
Resolution: An Introspection
PATTNAIK, S. K. KAMILA2, G. S. ROY3,R.
DAS4, N. K. SHARMA5
Samanta Planetarium, Bhubaneswar, Orissa (INDIA),
of Physics, ITER, Bhubaneswar, Orissa (INDIA),
of Physics, Govt. (Auto) college, Bhawanipatana, Orissa (INDIA)
College, Cuttack, Orissa (INDIA)
resolution is not unambiguously defined, it is interpreted in
many ways by many researchers. In this paper, which reviews the
concept of optical resolution, a number of these interpretations
are discussed. A discussion of resolution preceded by the
classical approach to the study of two-point resolution are
dealt. The well-known resolution
criterion of Sparrow and Rayleigh resolution criterion are
surveyed, Only an ideal imaging system can reproduce an
infinitesimally small point object as an infinitesimally small
point image. An ideal imaging system is one in which diffraction
and aberrations are absent. A point-source object can be
represented mathematically by a delta function called the “Point
Spread Function (PSF)”. This spread of light in the image is
determined jointly by diffraction, aberration and also the
non-uniformity of amplitude and/or phase transmission specified
by the pupil function, if, particularly, the optical system is
apodised. Resolution also depends on the coherence conditions of
illuminance. Light waves from two distinct self-luminous point
sources are incoherent, as is true for double stars imaged by a
telescope. Incoherent imaging is linear in intensity. Therefore
the intensity distribution produced by two incoherent point
sources is obtained by adding their separate intensity
diffraction patterns. Apodization processes narrowing the main
lobe of the point-spread function improve the resolution in the
sense of the classical criteria. However, these criteria are
based on calculated images for which in principle no obvious
limit to resolution exists. It remains to be seen if apodization
still enhances resolution if it is applied to detect images.
PATTNAIK, S. K. KAMILA, G. S. ROY, R. DAS, N. K. SHARMA,
Two Point Resolution: An Introspection, Researcher.
2011;3(2):66-72]. (ISSN: 1553-9865).
Two-point resolution, point object, degree of coherence,
Resolution & coherence, apodization
Study results of microbial cultures isolated from patients
hospitalized in different wards of hospitals in Khuzestan, Ahvaz
Abdullah Sarami1, Morosh2,
Nasser bahrevar3, *Tayeb Saki Nejad4
1 - Specialist Infectious Diseases and
2- Infection Control Nurse
3 - Health Engineer
Assistant Professor, Islamic
(Design and analysis of statistics)
A microbiological culture, or microbial culture,
is a method of multiplying microbial organisms by letting them
reproduce in predetermined culture media under controlled
infections, nosocomial infections due to medical care that
patients performed within 24 hours after the start of admission
to 72 hours after discharge from the hospital to be with them,
are applicable. Again according to some developing countries 5
to 10 percent of patients admitted to these infections may be
affected. This issue is being raised because the control of
nosocomial infections as a global priority and to identify their
coordinates in one of the hospitals was conducted.
Tayeb Saki Nejad.
Study results of
microbial cultures isolated from patients hospitalized in
different wards of hospitals in Khuzestan, Ahvaz 2008-9(IRAN).
Researcher. 2011;3(2):73-74]. (ISSN: 1553-9865).
microbes isolated, Patients, culture
some heavy metals pollution on Oreochromis niloticus in
River Nile and Ismailia Canal
Moustafa1 Abd El Aziz M..1, Abd
El Meguid A. Z. 1 and Hussien A. M. Osman 2
Fish Disease and Management, Faculty of Veterinary Medicine,
Department of hydrobiology National Research Center Giza, Egypt
Water and Nile Tilapia fish samples were collected from
industrial localities in the River Nile at "Helwan, El muasaia,
shubra El Khima" and from Ismailia canal at (Moustord, Ceriakos,
Abu zaabal) The samples were examined for the presence of heavy
metals "lead, mercury and cadmium" using atomic adsorption
spectrophotometer. On comparing our Results with the recommended
standard levels of these metals in water it revealed that the
levels of these metals in River Nile and Ismailia canal were
found at critical limits that constitute a great potential
health hazards. Also the analysis of Nile Tilapia fish collected
from the same areas & on comparing with the recommended levels
Revealed that these metals were found at serious concentrations
many times higher than the levels of such metals in water which
indicated that Bioaccumulation of these metals occurred which
represents a potential health hazard for humans consuming these
fishes. The effluents which are directly thrown down to these
water by many factories found along the course of River Nile
Ismailia canal are considered the main source of these metals.
M. Moustafa Abd El Aziz M, Abd El Meguid A. Z and Hussien A. M.
Osman. Evaluation of some heavy metals pollution on
Oreochromis niloticus in River
Nile and Ismailia
Researcher. 2011;3(2):75-79]. (ISSN: 1553-9865).
River Nile – Ismailia canal – Heavy metals – Pollution – Nile
Microbiological Studies on Cultural, Physiological
Characteristics and Antimicrobial Activities of Streptomyces
Botany and Microbiology Department, Faculty of Science (Boys),
Al-Azhar University, Cairo, Egypt. The present address:
Biotechnology Department. Faculty of Science and Education- Al-Khurmah,
Taif University; KSA.
Biotechnology Dept. Faculty of Science - Taif University; KSA.
Department of Botany, Faculty of Science, Zagazig University,
collected from different localities in Egypt. One of the
actinomycete cultures (AZ-13Zc) from three cultures was found to
produce a wide spectrum antimicrobial agent (anti-Gram-positive
and Gram-negative bacteria and unicellular fungi). The
actinomycete AZ-13Zc could be isolated from a soil sample
collected from Zefta
district, Egypt. From the taxonomic features, the actinomycete
isolate AZ-13Zc matches with Streptomyces cyaneus in the
morphological, physiological and biochemical characters. Thus,
it was given the suggested name Streptomyces cyaneus-AZ-13Zc.
The parameters controlling the biosynthetic process of
antimicrobial agent formation including: inoculum size,
different pH values, different temperatures, different
incubation period, and different carbon and nitrogen sources,
potassium nitrate, K2HPO4, MgSO4.7H2O
and KCl concentrations were fully investigates.
[Atta H.M., El-Sehrawi
M.H., Awny N.M., El-Mesady N.I. Microbiological
Studies on Cultural, Physiological Characteristics and
Antimicrobial Activities of Streptomyces Cyaneus-AZ-13Zc.
Researcher. 2011;3(2):80-90]. (ISSN: 1553-9865).
Streptomyces cyaneus, Cultural, physiological activities,
Study of hydrogeological potential in
the basement areas in eastern
Chad: a case study of Ouaddaï-Biltine
Oursingbé & Zhonghua Tang
Hydrogeology and Water Resources, School of Environment Studies
China University of
Geosciences, 430074-Wuhan, Lumo Road 388, Hubei, China,
This study carries on the assessing of the productivity of fissured
aquifers of the regions of
Biltine from an approach which takes into account climate variability,
water balance, the thickness of regolith, the total depth of
boreholes and the exploitation flow rates. An analysis of the
hydrogeological parameters of 659 boreholes drillings was
carried out. The results
unfavourable zones as well as principal
fractures direction associated with the recently opening of the
Atlantic rift and the
Red Sea. From this analysis it shows up clearly that the preferential
targets of positive boreholes in the area of Ouaddaï-Biltine are
the fractures with wide lengths oriented N60°E and N90°E.
The analysis of
of water inflows made it possible to highlight the presence of a
shallow aquifer whose productive levels are located at a depth
of 20 to 40m and a second productive level at a depth of 50m and
more. The granite formations which constitute the majority of
the geological formations are in general most productive. The
best results are located in the pink granites and rhyolites and
gray granite. The average flow rates of positive boreholes are
range between 1.4 and 1.6m3/h in the north and move
between 3 and 4.4m3/h in the south. These results
to make known the
potentialities. They direct
hydrogeological prospection for an economic boreholes
establishment in this region.
[Massing Oursingbé, Zhonghua Tang. Study of hydrogeological potential in the
basement areas in eastern Chad: a case study of Ouaddaï-Biltine.
Researcher. Researcher. 2011;3(2):91-100]. (ISSN: 1553-9865).
Borehole drilling, success rates, rural water supply, basement,
study of fixed drug eruption
Abd El Fattah Seleit*1,
Mohamed Ahmed Basha1, Nansy
Youssef Asaad2, Ola
of Dermatology and Andrology1 and Pathology2,
Faculty of Medicine Menoufiya University
Background: Fixed drug eruption (FDE) is a common drug induced
dermatosis that can be caused by a variety of drugs. Although
effector and regulatory T cells play a role in progression and
resolution of FDE, little in vivo data exist regarding T cell
dynamics in its pathogenesis. Objectives: To through
light on the immunopathogenesis of FDE through studying the
participation of CD8+, CD4+ T cells and HLA-DR antigen in the
pathogenesis of lesions. The role of serum Ca was studied.
Patients and methods: Thirty skin biopsy specimens from FDE skin
lesions were used (16 active lesions& 14 healed lesions). Thirty
biopsy specimens from thirty age and sex matched healthy
subjects were used as a control group. Histopathological
examination of hematoxylin& eosin-stained sections included
analysis and scoring of histopathological parameters was done.
Expression of CD4, CD8 and HLA-DR antigens was examined
immunohistochemically. Blood samples were collected from
patients and control subjects for assesment of serum calcium.
Results: Active lesions showed
interface dermatitis and dermal inflammatory infiltrate.
Positive immunostaining was observed in both epidermis and
dermis for HLA-DR, CD4 and CD8 antigens. Healed lesions showed
epidermal atrophy and dermal inflammatory infiltrate. Positive
immunostaining was observed in both epidermis and dermis for HLA-DR,
CD4 and CD8 antigens. Such results were absent in control
sections. Both total and ionized Ca2+ were significantly lower
in patients than control subjects.
Conclusions: Activation of T cells residing in resting
FDE lesions by ingestion of the causative drug results in
epidermal injury possibly through the production of IFN-γ.
Abd El Fattah Seleit,
Mohamed Ahmed Basha, Nansy Youssef
Asaad, Ola Ahmed Amin.
Immunopathologic study of fixed drug eruption.
Researcher. 2011;3(2):101-109]. (ISSN: 1553-9865).
FDE, CD4+T cells, CD8+T cells, IFN-γ
prolifera ameliorates the impact of dyslipidemia – induced
oxidative stress and inflammation.
Hanna, H. Ahmed1,*,
Mohga, S. Abdalla2, Emad, F. Eskander1,
Manal, F. Al-Khadragy3, Mary, N. Massoud1
1: Hormones Department ,
National Research Centre, Dokki,
2: Chemistry Department,
Faculty of Science,
3: Zoology and Entomology
Department Faculty of Science,
This study was undertaken to investigate the potential role of
Caulerpa prolifera methanolic extract in management of
dyslipidemia and its complications in female rats. Forty adult
Sprague Dawley rats were enrolled in the present study and they
were assigned as lean control group; dyslipidemic control group;
lean rats treated with C.prolifera methanolic extract (50 mg/kg
b.wt), and dyslipidemic rats treated with C.prolifera methanolic
extract for 4 months. The results revealed that the treatment of
dyslipidemic rats with C.prolifera resulted in significant
reduction in plasma cholesterol, triglycerides, LDL level
accompanied with significant elevation in plasma HDL level.
Also, C.prolifera extract induced significant deacrease in serum
MDA and inorganic free radical (NO) levels in dyslipidemic rats.
Furthermore, Administration of C.prolifera extract in
dyslipidemic animals produced significant depletion in serum
leptin and TNF-α level associated with significant rise in serum
adiponectin level. These results indicated that C.prolifera
extract has played a vital role in ameliorating dyslipidemia and
its complications particularly oxidative stress and
inflammation. These findings may provide new concept for
development of effective natural therapy for dyslipidemia and
its associated serious complications.
H. Ahmed, Mohga,
Emad, F. Eskander, Manal, F. Al-Khadragy, Mary, N. Massoud.
Caulerpa prolifera ameliorates the impact of dyslipidemia –
induced oxidative stress and inflammation.
Researcher. 2011;3(2):110-119]. (ISSN: 1553-9865).
Dyslipidemia, Nitric oxide, oxidative stress, antioxidant,
And Immunological Assessment Of Activity In Graves'
Abdel-Samee1, Elhadidy Mohammed Elhadidy2,
Manal Mostafa Tarshoby2, Mohammed Sherif Abdel-Gawad2,
Sahar Mostafa Tarshoby3
.Clinical Pathology Department, Faculty of Medicine, Mansoura
2. Internal Medicine Department, Faculty of Medicine, Mansoura
3. Ophthalmology Department, Faculty of Medicine, Mansoura
is an autoimmune disorder, which is characterized by
hyperthyroidism, goiter and in some cases ophthalmopathy.
Patients with serious inflammatory Graves' ophthalmopathy should
be treated with anti-inflammatory drugs or radiotherapy to
prevent complications, while those with extraocular muscle
dysfunction at the stage of fibrosis and proptosis does not
generally respond well to corticosteroid, thus treated
surgically. The aim of this work is to know whether a patient
has active or quiescent Graves' ophthalmopathy as it is often
difficult however to distinguish inflammatory from non
inflammatory Graves' disease. The present study compromised 40
patients with Graves' ophthalmopathy selected from Out Patient
Clinic in Mansoura University Hospital, and 15 healthy
volunteers as control. All control subjects and patients were
subjected to the following: Complete history taking, complete
general examination, thyroid examination and neurological
examination, Clinical activity scoring, Orbital ultrasonography.
Thyroid function test: T3, T4, TSH, sICAM-1,
serum level, CD3, CD4, CD8 in the peripheral blood. Using
orbital U.S. 70% of our patients with active Graves'
ophthalmopathy have a low extraocular muscle reflectivity. Also
there were significant elevation of CAS, sICAM-1, IL-2 and
patient with positive U.S. compared to those with negative U.S.
in active Graves ophthalmopathy. Serum levels of sICAM-1 were
significantly high in patients with Graves' disease than
controls. And it is higher in patients with active Graves'
ophthalmopathy. In addition, there was significant high level of
both IL-2 and
patients with active Graves' ophthalmopathy than inactive one.
Also they positively correlated with sICAM-1 level and CAS. CAS
is a good tool for differentiation between active and inactive
Graves' ophthalmopathy and can be strengthened by orbital U.S.
as well as sICAM-1, IL-2 and
gIFN. On the
other hand, T cell subsets were found to be of little help in
differentiation between active and inactive disease status.
Abdel-Samee, Elhadidy Mohammed Elhadidy, Manal Mostafa Tarshoby,
Mohammed Sherif Abdel-Gawad, Sahar Mostafa Tarshoby: Assessment
of Graves' opthalmopathy activity. Researcher.
2011;3(2):120-129]. (ISSN: 1553-9865).
Graves' opthalmopathy, sICAM, Interleukin 2, proptosis, gamma
The manuscripts in this
issue were presented as online first for peer-review starting
from December 16, 2010.
All comments are
back issues of the Researcher, click here.
Emails: email@example.com; firstname.lastname@example.org