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New York Science Journal
(N Y Sci J)
ISSN 1554-0200 (print); ISSN 2375-723X (online),
doi prefix: 10.7537, Monthly
Volume 19 -
Number 3 (Cumulated No. 205); 25, 2026
Cover (pdf),
Cover,
Introduction,
Contents,
Call for
Papers
The following manuscripts are presented as online first for peer-review, starting from March 2, 2026.
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CONTENTS
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Authors /Abstracts
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Sequential Nephron Blockade with Metolazone for Decongestion in
Advanced Decompensated Heart Failure
Arafat M. Abd Elrahman, and Muhammad A. Alghorayeb
National Heart Institute, Giza, Egypt
Corresponding email:
Arafatmahmoud88@yahoo.com
Abstract: Background:
Congestion-driven hospitalization remains a major cause of
morbidity and mortality in patients with acute decompensated
heart failure (ADHF). Diuretic resistance frequently limits the
effectiveness of loop diuretics, prompting the use of sequential
nephron blockade with thiazide-like diuretics such as
metolazone. Objective assessment of decongestion using
radiographic markers may improve evaluation of treatment
response. Objectives: To compare diuretic response,
radiographic and clinical decongestion, renal safety, and
short-term clinical outcomes in patients with advanced
decompensated heart failure treated with intravenous loop
diuretics alone versus loop diuretics plus metolazone.
Methods: This retrospective observational cohort study
included 43 patients with chronic heart failure with reduced
ejection fraction hospitalized for ADHF. Patients were treated
with intravenous Frusemide alone (n = 23) or in combination with
metolazone (n = 20). Diuretic efficiency, urine output, weight
change, congestion score index (CSI) derived from chest
radiography, renal function, electrolyte changes, loop diuretic
dose at discharge, and survival were evaluated. Results:
Patients receiving metolazone demonstrated significantly greater
diuretic efficiency (958.00 ± 156.46 mL/40 mg Frusemide vs,
614.35 ± 281.66 mL/40 mg; p < 0.05), higher urine output
(2950.00 ± 591.61 mL vs 2165.22 ± 939.83 mL; p < 0.05), and
larger reductions in body weight compared with Frusemide alone
(−5.96 ± 2.20 kg) vs., −3.65 ± 1.38 kg; p < 0.05).(all p <
0.05). Radiographic decongestion was more pronounced in the
metolazone group, with a significantly greater reduction in CSI
at discharge (1.15 ± 0.37 vs 0.74 ± 0.54; p < 0.05). The
metolazone group required a significantly lower loop diuretic
dose at discharge (252.39 ± 137.05 mg; p < 0.05), without an
increase in renal dysfunction or electrolyte disturbances.
Although survival was numerically longer in the metolazone
group, the difference was not statistically significant.
Conclusion: In patients with advanced ADHF, adjunctive
metolazone therapy was associated with improved diuretic
efficiency, more effective radiographic and clinical
decongestion, and lower loop diuretic requirements at discharge,
without compromising renal safety.
[Arafat M. Abd Elrahman, and Muhammad A. Alghorayeb
Sequential Nephron Blockade with Metolazone for Decongestion in
Advanced Decompensated Heart Failure.
N Y Sci J
2026;19(3):1-9]. ISSN 1554-0200
(print); ISSN 2375-723X (online).
http://www.sciencepub.net/newyork.
01. Doi:
10.7537/marsnys190326.01
Keywords:
diuretic resistance; decongestion; heart Failure; metolazone;
radiological congestion score index (RCSI) |
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Evaluation of Biogas Production from Co-Digestion of Kitchen
Waste and Cow Dung
Greg, M.(1), Tanko, B.(2)
and Fidelis, F.(3)
(1), (3)
Department of Civil Engineering, Taraba State University,
Jalingo, Nigeria
(2)Department
of Agricultural and Biosystems Engineering, Taraba State
University, Jalingo, Nigeria.
Email:
engrtesenrubi@gmail.com
Phone:
+234 08033070655
Abstract:
Improper disposal of plant and animal waste poses significant
risks to environmental and public health, including the
contamination of water sources with pathogens and chemicals.
This study addresses this critical issue by evaluating the
potential of converting these wastes into a renewable energy
source: biogas. The research focuses on the production of biogas
from the digestion and co-digestion of readily available kitchen
waste and cow dung within the Jalingo metropolis, Taraba State,
Nigeria. Through a systematic evaluation of digester systems,
this study compares the efficiency of digestion and co-digestion
methods. The primary objective is to determine the most suitable
waste materials and methods for optimal biogas production.
Co-digestion was found to substantially increase the biogas
yields. By utilizing these local waste resources, the project
aimed to not only mitigate environmental contamination but also
provide a cost-effective, renewable energy solution for the
community. The findings of this study are expected to offer a
sustainable waste management model that can reduce greenhouse
gas emissions, enhance energy independence, and create economic
opportunities through the valorization of waste.
[Greg, M., Tanko, B. and Fidelis, F. Evaluation of Biogas
Production from Co-Digestion of Kitchen Waste and Cow Dung.
N Y Sci J
2026;19(3):10-15]. ISSN 1554-0200
(print); ISSN 2375-723X (online).
http://www.sciencepub.net/newyork.
02. Doi:
10.7537/marsnys190326.02
KEY WORDS:
Co-Digestion; Kitchen Waste; Cow Dung; Biogas; Anaerobic |
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THE ROLE OF CLIMATE CHANGE ON GLOBAL FOOD SECURITY
ASUERIMEN P.G1, OSARENMWINDA I. E2,
AFOLABI A. E3, OLANIYAN C. K4, OKO E5,
NWACHUKWU I. M6, IBIRONKE H. O7.EGUSA D8
1Department of Geography and
Planning, Abia State University. Abia State, Nigeria.
2Department of Industrial
Chemistry, University of Benin, Edo State, Nigeria.
3Department of Plant Science
University of Cambridge, Cambridge UK
4Department of Agricultural
Economics, Ladoke Akintola University of Technology, Oyo State
Nigeria.
5Department
of Natural Resources and Environmental sciences, Alabama
Agricultural and Mechanical University, Huntsville, Alabama. USA
6Department of Agricultural
Economics, Federal University of Agriculture Abeokuta, Ogun
State Nigeria.
7Department of Crop and
Horticultural science, University of Ibadan, Oyo State Nigeria.
8Department of Microbiology,
University of Benin, Edo State, Nigeria
Corresponding Author: asuerimenprecious@gmail.com
ABSTRACT:
Climate change poses a significant threat to global food
security, impacting crop yields, food availability, health and
access to nutrition. Rising temperatures, altered precipitation
patterns, and increased frequency of extreme weather events are
altering the conditions under which crops are grown, livestock
are raised, and food systems operate. This review examines the
current state of knowledge on the impacts of climate change on
global food security, highlighting the effects on crop yields,
food prices, and human nutrition. We discuss the potential
adaptation and mitigation strategies that can help reduce the
vulnerability of food systems to climate change, including
climate smart agriculture, improved irrigation management, crop
insurance, geoinformatics and enhanced food storage and
distribution systems. Our analysis reveals that climate change
affects not only crop productivity but also food access,
utilization, and stability, with far reaching implications for
human well being, particularly in vulnerable populations. We
emphasize the need for a comprehensive approach to addressing
the impacts of climate change on food security, including
policy, technological, and institutional innovations that
support climate resilient food systems. This review aims to
inform policymakers, researchers, and practitioners about the
complex relationships between climate change and food security,
and to identify opportunities for building more resilient food
systems in the face of a changing climate.
[ASUERIMEN P.G, OSARENMWINDA I.
E, AFOLABI A. E, OLANIYAN C. K, OKO E, NWACHUKWU I. M6,
IBIRONKE H. O7.EGUSA D.
THE ROLE OF CLIMATE CHANGE ON GLOBAL FOOD SECURITY.
N Y Sci J
2026;19(3):16-26]. ISSN 1554-0200
(print); ISSN 2375-723X (online).
http://www.sciencepub.net/newyork.
03. Doi:
10.7537/marsnys190326.03
Keyword:
Public Health;
Climate
Change; Food Security; Crop Yields Adaptation Strategies;
Vulnerable Populations |
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The manuscripts in
this issue were presented as online first for peer-review.
All comments are
welcome: newyorksci@sciencepub.net,
or contact with
author(s) directly.
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Science Journal, click
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